• Target：
• THIC

• Fields：
• >>Fatty acid degradation;>>Valine, leucine and isoleucine degradation;>>Lysine degradation;>>Tryptophan metabolism;>>Pyruvate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Butanoate metabolism;>>Terpenoid backbone biosynthesis;>>Metabolic pathways;>>Carbon metabolism;>>Fatty acid metabolism;>>Fat digestion and absorption

• Gene Name：
• ACAT2 ACTL

• Protein Name：
• THIC

• Human Gene Id：
• 39

• Human Swiss Prot No：
• Q9BWD1

• Mouse Gene Id：
• 110460

• Mouse Swiss Prot No：
• Q8CAY6

• Rat Gene Id：
• 308100

• Rat Swiss Prot No：
• Q5XI22

• Immunogen：
• Synthesized peptide derived from human THIC AA range: 320-370

• Specificity：
• This antibody detects endogenous levels of THIC at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 44kD

• Background：
• The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014],

• Function：
• catalytic activity:2 acetyl-CoA = CoA + acetoacetyl-CoA.,similarity:Belongs to the thiolase family.,subunit:Homotetramer.,

• Subcellular Location：
• Cytoplasm, cytosol .

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