• Target：
• FCGRN

• Gene Name：
• FCGRT FCRN

• Protein Name：
• FCGRN

• Human Gene Id：
• 2217

• Human Swiss Prot No：
• P55899

• Mouse Gene Id：
• 14132

• Mouse Swiss Prot No：
• Q61559

• Rat Gene Id：
• 29558

• Rat Swiss Prot No：
• P13599

• Immunogen：
• Synthesized peptide derived from human FCGRN AA range: 146-196

• Specificity：
• This antibody detects endogenous levels of FCGRN at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 40kD

• Background：
• This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009],

• Function：
• function:Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.,similarity:Belongs to the immunoglobulin superfamily.,subunit:FcRn complex consist of two subunits: p51, and p14 which is equivalent to beta-2-microglobulin. It forms an MHC class I-like heterodimer.,

• Subcellular Location：
• Cell membrane ; Single-pass type I membrane protein . Endosome membrane .

• Expression：
• Expressed in full-term placenta, heart, lung, liver, muscle, kidney, pancreas, and both fetal and adult small intestine.

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