K1731 rabbit pAb

    • Catalog No.:YT6425
    • Applications:IHC;IF
    • Reactivity:Human;Mouse;Rat
      • Target:
      • K1731
      • Gene Name:
      • KIAA1731
      • Protein Name:
      • K1731
      • Human Swiss Prot No:
      • Q9C0D2
      • Mouse Swiss Prot No:
      • Q8BQ48
      • Immunogen:
      • Synthesized peptide derived from human K1731 AA range: 208-258
      • Specificity:
      • This antibody detects endogenous levels of K1731 at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:50-200. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 286kD
      • Function:
      • sequence caution:Translation N-terminally shortened.,similarity:Contains 7 LRR (leucine-rich) repeats.,
      • Subcellular Location:
      • Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton . Associates with both of the converted centrioles during G1 but becomes more enriched at the newly formed daughter (or unconverted) centrioles during S, G2, and early M phases (PubMed:25131205, PubMed:32060285). In early S phase, localized at the procentriolar microtubule wall and enriched at the proximal ends of the centrioles in CENPJ- and CEP135-dependent manner (PubMed:27185865). Colocalizes with SASS6 and CEP250 proteins (PubMed:25131205). Colocalizes with CEP135 and CEP192 at the centrosomes (PubMed:27185865). Associates with interphase microtubules and mitotic spindles (PubMed:
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).