• Target：
• TM165

• Gene Name：
• TMEM165 TPARL

• Protein Name：
• TM165

• Human Gene Id：
• 55858

• Human Swiss Prot No：
• Q9HC07

• Mouse Gene Id：
• 21982

• Mouse Swiss Prot No：
• P52875

• Rat Gene Id：
• 100911646

• Rat Swiss Prot No：
• Q4V899

• Immunogen：
• Synthesized peptide derived from human TM165 AA range: 68-118

• Specificity：
• This antibody detects endogenous levels of TM165 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 36kD

• Background：
• This gene encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],

• Function：
• similarity:Belongs to the UPF0016 family.,

• Subcellular Location：
• Golgi apparatus membrane ; Multi-pass membrane protein . Golgi apparatus, trans-Golgi network membrane. Lysosome membrane. Early endosome membrane. Late endosome membrane.

• Expression：
• Ubiquitously expressed.

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