• Target：
• FXYD3

• Gene Name：
• FXYD3 MAT8 PLML

• Protein Name：
• FXYD3

• Human Gene Id：
• 5349

• Human Swiss Prot No：
• Q14802

• Mouse Gene Id：
• 17178

• Mouse Swiss Prot No：
• Q61835

• Rat Gene Id：
• 116831

• Rat Swiss Prot No：
• P59645

• Immunogen：
• Synthesized peptide derived from human FXYD3 AA range: 15-65

• Specificity：
• This antibody detects endogenous levels of FXYD3 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1：50-200. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 10kD

• Background：
• This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008],

• Function：
• function:Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May be a modulator capable of activating endogenous oocyte channels.,miscellaneous:Marker of a cell type preferentially transformed by neu or ras oncoprotein.,similarity:Belongs to the FXYD family.,tissue specificity:Expressed in a subset of human breast tumors.,

• Subcellular Location：
• Cell membrane ; Single-pass type I membrane protein .

• Expression：
• Isoform 1: Expressed mainly in differentiated cells (at protein level). Isoform 2: Expressed mainly in undifferentiated cells (at protein level).

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