FXYD3 rabbit pAb
- Catalog No.:YT6405
- Applications:IHC;IF
- Reactivity:Human;Mouse;Rat
- Target:
- FXYD3
- Gene Name:
- FXYD3 MAT8 PLML
- Protein Name:
- FXYD3
- Human Gene Id:
- 5349
- Human Swiss Prot No:
- Q14802
- Mouse Gene Id:
- 17178
- Mouse Swiss Prot No:
- Q61835
- Rat Gene Id:
- 116831
- Rat Swiss Prot No:
- P59645
- Immunogen:
- Synthesized peptide derived from human FXYD3 AA range: 15-65
- Specificity:
- This antibody detects endogenous levels of FXYD3 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 10kD
- Background:
- This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008],
- Function:
- function:Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May be a modulator capable of activating endogenous oocyte channels.,miscellaneous:Marker of a cell type preferentially transformed by neu or ras oncoprotein.,similarity:Belongs to the FXYD family.,tissue specificity:Expressed in a subset of human breast tumors.,
- Subcellular Location:
- Cell membrane ; Single-pass type I membrane protein .
- Expression:
- Isoform 1: Expressed mainly in differentiated cells (at protein level). Isoform 2: Expressed mainly in undifferentiated cells (at protein level).
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).