MICA1 rabbit pAb
- Catalog No.:YT6400
- Applications:WB;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- MICA1
- Gene Name:
- MICAL1 MICAL NICAL
- Protein Name:
- MICA1
- Human Gene Id:
- 64780
- Human Swiss Prot No:
- Q8TDZ2
- Mouse Gene Id:
- 171580
- Mouse Swiss Prot No:
- Q8VDP3
- Rat Gene Id:
- 294520
- Rat Swiss Prot No:
- D3ZBP4
- Immunogen:
- Synthesized peptide derived from human MICA1 AA range: 155-205
- Specificity:
- This antibody detects endogenous levels of MICA1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 117kD
- Background:
- This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
- Function:
- cofactor:FAD .,domain:The C-terminal coiled coil part contains the plexin-interacting region.,function:May be a cytoskeletal regulator that connects NEDD9 to intermediate filaments.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 LIM zinc-binding domain.,subunit:Associates with the SH3 domain of NEDD9. Interacts with VIM and PLXNA3. Interacts with RAB1B.,tissue specificity:Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells.,
- Subcellular Location:
- Cytoplasm. Cytoplasm, cytoskeleton. Midbody . Accumulates transiently at the abscission site before abscission occurs. .
- Expression:
- Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).