• Target：
• MICA1

• Gene Name：
• MICAL1 MICAL NICAL

• Protein Name：
• MICA1

• Human Gene Id：
• 64780

• Human Swiss Prot No：
• Q8TDZ2

• Mouse Gene Id：
• 171580

• Mouse Swiss Prot No：
• Q8VDP3

• Rat Gene Id：
• 294520

• Rat Swiss Prot No：
• D3ZBP4

• Immunogen：
• Synthesized peptide derived from human MICA1 AA range: 155-205

• Specificity：
• This antibody detects endogenous levels of MICA1 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 117kD

• Background：
• This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

• Function：
• cofactor:FAD .,domain:The C-terminal coiled coil part contains the plexin-interacting region.,function:May be a cytoskeletal regulator that connects NEDD9 to intermediate filaments.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 LIM zinc-binding domain.,subunit:Associates with the SH3 domain of NEDD9. Interacts with VIM and PLXNA3. Interacts with RAB1B.,tissue specificity:Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells.,

• Subcellular Location：
• Cytoplasm. Cytoplasm, cytoskeleton. Midbody . Accumulates transiently at the abscission site before abscission occurs. .

• Expression：
• Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells.

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