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- HDA11 rabbit pAb
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HDA11 rabbit pAb
- Catalog No.:YT6387
- Applications:WB
- Reactivity:Human;Mouse
- Fields:
- >>Neutrophil extracellular trap formation;>>Alcoholism;>>Viral carcinogenesis
- Immunogen:
- Synthesized peptide derived from human HDA11 AA range: 170-220
- Specificity:
- This antibody detects endogenous levels of HDA11 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 38kD
- Background:
- This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009],
- Function:
- catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.,function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.,miscellaneous:Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.,sequence caution:Translated as Gln.,similarity:Belongs to the histone deacetylase family.,subcellular location:Predominantly nuclear.,subunit:Interacts with HDAC6.,tissue specificity:Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.,
- Subcellular Location:
- Nucleus .
- Expression:
- Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.
![](/uploadfiles/PIC/YT6387wb-2019.jpg)
- Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night