S23A1 rabbit pAb
- Catalog No.:YT6323
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- S23A1
- Fields:
- >>Vitamin digestion and absorption
- Gene Name:
- SLC23A1 SVCT1 YSPL3
- Protein Name:
- S23A1
- Human Gene Id:
- 9963
- Human Swiss Prot No:
- Q9UHI7
- Mouse Gene Id:
- 20522
- Mouse Swiss Prot No:
- Q9Z2J0
- Rat Gene Id:
- 50621
- Rat Swiss Prot No:
- Q9WTW7
- Immunogen:
- Synthesized peptide derived from human S23A1 AA range: 237-287
- Specificity:
- This antibody detects endogenous levels of S23A1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 66kD
- Background:
- The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
- Function:
- alternative products:Experimental confirmation may be lacking for some isoforms,function:Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.,miscellaneous:Treatment with the protein kinase C stimulator PMA results in a 10-fold decrease in ascorbate accumulation in transfected cells.,PTM:Phosphorylated.,similarity:Belongs to the xanthine/uracil permease family. SLC23A subfamily.,tissue specificity:Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.,
- Subcellular Location:
- Cell membrane ; Multi-pass membrane protein .
- Expression:
- Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night