DGLB rabbit pAb

    • Catalog No.:YT6321
    • Applications:WB
    • Reactivity:Human;Mouse;Rat
      • Target:
      • DGLB
      • Fields:
      • >>Retrograde endocannabinoid signaling;>>Aldosterone synthesis and secretion
      • Gene Name:
      • DAGLB
      • Protein Name:
      • DGLB
      • Human Swiss Prot No:
      • Q8NCG7
      • Mouse Swiss Prot No:
      • Q91WC9
      • Immunogen:
      • Synthesized peptide derived from human DGLB AA range: 616-666
      • Specificity:
      • This antibody detects endogenous levels of DGLB at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 74kD
      • Function:
      • cofactor:Calcium.,enzyme regulation:Inhibited by p-hydroxy-mercuri-benzoate and HgCl(2), but not to PMSF. Also inhibited by RHC80267, a drug that blocks 2-AG formation.,function:Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,
      • Subcellular Location:
      • Cell membrane ; Multi-pass membrane protein .
      • Products Images
      • Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night