Flotillin-1 Polyclonal Antibody

    • Catalog No.:YT6292
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Flotillin-1
      • Fields:
      • >>Insulin signaling pathway
      • Gene Name:
      • FLOT1
      • Protein Name:
      • Flotillin-1
      • Human Swiss Prot No:
      • O75955
      • Immunogen:
      • Synthesized peptide derived from human Flotillin-1
      • Specificity:
      • This antibody detects endogenous levels of human Flotillin-1
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000, ELISA(peptide)1:5000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • Flotillin-1
      • Observed Band(KD):
      • 48kD
      • Background:
      • This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
      • Function:
      • function:May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.,similarity:Belongs to the band 7/mec-2 family. Flotillin subfamily.,subcellular location:Membrane-associated protein of caveolae. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2.,
      • Subcellular Location:
      • Cell membrane; Peripheral membrane protein . Endosome . Membrane, caveola ; Peripheral membrane protein . Melanosome . Membrane raft . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Membrane-associated protein of caveola (By similarity). .
      • Expression:
      • Adipose tissue,Adrenal gland,Lung,Peripheral blood leukocyte,Umbilical cord blood,
      • Products Images
      • Western blot analysis of various lysates, primary antibody was diluted at 1:1000, 4° over night, secondary antibody(cat: RS23920)was diluted at 1:10000, 37° 1hour.