• Target：
• SEC61B

• Fields：
• >>Protein export;>>Protein processing in endoplasmic reticulum;>>Phagosome;>>Vibrio cholerae infection

• Gene Name：
• SEC61B

• Protein Name：
• SEC61B

• Human Gene Id：
• 10952

• Human Swiss Prot No：
• P60468

• Immunogen：
• Synthesized peptide derived from human SEC61B AA range: 30-110

• Specificity：
• This antibody detects endogenous levels of human SEC61B

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:50-200, ELISA(peptide)1:5000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Protein transport protein Sec61 subunit beta

• Background：
• The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008],

• Function：
• function:Necessary for protein translocation in the endoplasmic reticulum.,similarity:Belongs to the SEC61-beta family.,subunit:Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma. Part of a complex composed of SEC61, SEC62 and SEC63. Interacts with SEC62.,

• Subcellular Location：
• Endoplasmic reticulum membrane ; Single-pass membrane protein .

• Expression：
• Brain,Embryonic kidney,Epithelium,Stomach mucosa,

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