Secretogranin-1 Polyclonal Antibody
- Catalog No.:YT6192
- Applications:IHC;IF;WB
- Reactivity:Human;Mouse;Rat
- Target:
- Secretogranin-1
- Gene Name:
- CHGB SCG1
- Protein Name:
- Secretogranin-1
- Human Gene Id:
- 1114
- Human Swiss Prot No:
- P05060
- Immunogen:
- Synthesized peptide derived from human Secretogranin-1
- Specificity:
- This antibody detects endogenous levels of human Secretogranin-1
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, WB 1:500-2000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Secretogranin-1 (Chromogranin-B;CgB;Secretogranin I;SgI) [Cleaved into: GAWK peptide;CCB peptide]
- Observed Band(KD):
- 78kD
- Background:
- This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009],
- Function:
- function:Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,PTM:Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.,similarity:Belongs to the chromogranin/secretogranin protein family.,subcellular location:Neuroendocrine and endocrine secretory granules.,tissue specificity:Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.,
- Subcellular Location:
- Secreted. Neuroendocrine and endocrine secretory granules.
- Expression:
- Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).