• Target：
• AFG3L2

• Fields：
• >>Spinocerebellar ataxia

• Gene Name：
• AFG3L2

• Protein Name：
• AFG3L2

• Human Gene Id：
• 10939

• Human Swiss Prot No：
• Q9Y4W6

• Mouse Gene Id：
• 69597

• Mouse Swiss Prot No：
• Q8JZQ2

• Immunogen：
• Synthesized peptide derived from human AFG3L2. at AA range: 744-793

• Specificity：
• AFG3L2 Polyclonal Antibody detects endogenous levels of AFG3L2

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000, ELISA 1:10000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein)

• Observed Band(KD)：
• 88kD

• Background：
• This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. [provided by RefSeq, Jul 2008],

• Function：
• cofactor:Binds 1 zinc ion per subunit .,function:Putative ATP-dependent protease.,similarity:In the C-terminal section; belongs to the peptidase M41 family.,similarity:In the N-terminal section; belongs to the AAA ATPase family.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Mitochondrion . Mitochondrion inner membrane ; Multi-pass membrane protein .

• Expression：
• Ubiquitous. Highly expressed in the cerebellar Purkinje cells.

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs