• Target：
• AVPR1A

• Fields：
• >>Calcium signaling pathway;>>Phospholipase D signaling pathway;>>Neuroactive ligand-receptor interaction;>>Vascular smooth muscle contraction

• Gene Name：
• AVPR1A

• Protein Name：
• AVPR1A

• Human Gene Id：
• 552

• Human Swiss Prot No：
• P37288

• Mouse Gene Id：
• 54140

• Mouse Swiss Prot No：
• Q62463

• Immunogen：
• Synthesized peptide derived from human AVPR1A. at AA range: 11-60

• Specificity：
• AVPR1A Polyclonal Antibody detects endogenous levels of AVPR1A

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000, ELISA 1:10000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Vasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor)

• Observed Band(KD)：
• 55kD

• Background：
• The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008],

• Function：
• function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.,miscellaneous:Differences in regional receptor expression in the brain as well as differences in social behavior may result from a highly variable repetitive sequence in the 5' flanking region of AVPR1A. One such allelic variant has been linked to autism.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Liver,Lung,

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