ATG10 Polyclonal Antibody
- Catalog No.:YT6005
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- ATG10
- Fields:
- >>Autophagy - other;>>Autophagy - animal
- Gene Name:
- ATG10 APG10L PP12616
- Protein Name:
- Ubiquitin-like-conjugating enzyme ATG10 (EC 6.3.2.-) (Autophagy-related protein 10) (APG10-like)
- Human Gene Id:
- 83734
- Human Swiss Prot No:
- Q9H0Y0
- Mouse Gene Id:
- 66795
- Mouse Swiss Prot No:
- Q8R1P4
- Immunogen:
- Synthetic peptide from human protein at AA range: 1-50
- Specificity:
- The antibody detects endogenous ATG10
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Ubiquitin-like-conjugating enzyme ATG10 (EC 6.3.2.-;Autophagy-related protein 10;APG10-like)
- Background:
- Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008],
- Function:
- function:Plays a role in autophagy (By similarity). ATG12-conjugating enzyme (E2-like enzyme), likely serves as an ATG5-recognition molecule.,similarity:Belongs to the ATG10 family.,subunit:Interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7.,
- Subcellular Location:
- Cytoplasm .
- Expression:
- Placenta,Testis,Thymus,Uterus,
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200
- Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200