PACAP Polyclonal Antibody
- Catalog No.:YT5998
- Applications:IHC;IF;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- PACAP
- Gene Name:
- PACAP HSPC190
- Protein Name:
- Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein) (pERp1) (Proapoptotic caspase adapter protein)
- Human Gene Id:
- 51237
- Human Swiss Prot No:
- Q8WU39
- Mouse Gene Id:
- 69816
- Mouse Swiss Prot No:
- Q9D8I1
- Immunogen:
- Synthetic peptide from human protein at AA range: 1-50
- Specificity:
- The antibody detects endogenous PACAP
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein;pERp1;Proapoptotic caspase adapter protein)
- Background:
- function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,
- Function:
- function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,
- Subcellular Location:
- [Isoform 1]: Endoplasmic reticulum lumen . Secreted .; [Isoform 2]: Cytoplasm . Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957).
- Expression:
- Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200