PACAP Polyclonal Antibody

    • Catalog No.:YT5998
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • PACAP
      • Gene Name:
      • PACAP HSPC190
      • Protein Name:
      • Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein) (pERp1) (Proapoptotic caspase adapter protein)
      • Human Swiss Prot No:
      • Q8WU39
      • Mouse Swiss Prot No:
      • Q9D8I1
      • Immunogen:
      • Synthetic peptide from human protein at AA range: 1-50
      • Specificity:
      • The antibody detects endogenous PACAP
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein;pERp1;Proapoptotic caspase adapter protein)
      • Background:
      • function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,
      • Function:
      • function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,
      • Subcellular Location:
      • [Isoform 1]: Endoplasmic reticulum lumen . Secreted .; [Isoform 2]: Cytoplasm . Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957).
      • Expression:
      • Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat.
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200