Abin-2 Polyclonal Antibody
- Catalog No.:YT5987
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- Abin-2
- Gene Name:
- TNIP2 ABIN2 FLIP1
- Protein Name:
- TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)
- Human Gene Id:
- 79155
- Human Swiss Prot No:
- Q8NFZ5
- Mouse Gene Id:
- 231130
- Mouse Swiss Prot No:
- Q99JG7
- Immunogen:
- Synthetic peptide from human protein at AA range: 61-110
- Specificity:
- The antibody detects endogenous Abin-2
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2;ABIN-2;Fetal liver LKB1-interacting protein)
- Background:
- This gene encodes a protein which acts as an inhibitor of NFkappaB activation. The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types. It may be involved in apoptosis of endothelial cells. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the X chromosome.[provided by RefSeq, May 2014],
- Function:
- function:Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation.,subunit:Interacts with STK11, TNFAIP3, IKBKG, NFKB1, MAP3K8 and RIPK1.,tissue specificity:Ubiquitously expressed in all tissues examined.,
- Subcellular Location:
- Cytoplasm . Nucleus .
- Expression:
- Ubiquitously expressed in all tissues examined.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human-cervical-cancer, antibody was diluted at 1:200