Eotaxin-2 Polyclonal Antibody
- Catalog No.:YT5959
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- Eotaxin-2
- Fields:
- >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway
- Gene Name:
- CCL24 MPIF2 SCYA24
- Protein Name:
- C-C motif chemokine 24 (CK-beta-6) (Eosinophil chemotactic protein 2) (Eotaxin-2) (Myeloid progenitor inhibitory factor 2) (MPIF-2) (Small-inducible cytokine A24)
- Human Gene Id:
- 6369
- Human Swiss Prot No:
- O00175
- Mouse Gene Id:
- 56221
- Mouse Swiss Prot No:
- Q9JKC0
- Immunogen:
- Synthetic peptide from human protein at AA range: 61-110
- Specificity:
- The antibody detects endogenous Eotaxin-2
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- C-C motif chemokine 24 (CK-beta-6;Eosinophil chemotactic protein 2;Eotaxin-2;Myeloid progenitor inhibitory factor 2;MPIF-2;Small-inducible cytokine A24)
- Background:
- This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2008],
- Function:
- function:Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.,online information:CCL24 entry,PTM:N-glycosylated.,similarity:Belongs to the intercrine beta (chemokine CC) family.,tissue specificity:Activated monocytes and activated T lymphocytes.,
- Subcellular Location:
- Secreted .
- Expression:
- Activated monocytes and activated T lymphocytes.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200