BMP-9 Polyclonal Antibody
- Catalog No.:YT5956
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- BMP-9
- Fields:
- >>Cytokine-cytokine receptor interaction
- Gene Name:
- GDF2 BMP9
- Protein Name:
- Growth/differentiation factor 2 (GDF-2) (Bone morphogenetic protein 9) (BMP-9)
- Human Gene Id:
- 2658
- Human Swiss Prot No:
- Q9UK05
- Mouse Gene Id:
- 12165
- Mouse Swiss Prot No:
- Q9WV56
- Immunogen:
- Synthetic peptide from human protein at AA range: 371-420
- Specificity:
- The antibody detects endogenous BMP-9
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Growth/differentiation factor 2 (GDF-2;Bone morphogenetic protein 9;BMP-9)
- Background:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016],
- Function:
- function:Could be involved in bone formation.,online information:GDF2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
- Subcellular Location:
- Secreted .
- Expression:
- Detected in blood plasma (at protein level).
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