CD297 Polyclonal Antibody
- Catalog No.:YT5943
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- CD297
- Gene Name:
- ART4 DO DOK1
- Protein Name:
- Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 4) (ARTC4) (Dombrock blood group carrier molecule) (Mono(ADP-ribosyl)transferase 4) (NAD(P)(+)--arginine ADP-ri
- Human Gene Id:
- 420
- Human Swiss Prot No:
- Q93070
- Mouse Gene Id:
- 109978
- Mouse Swiss Prot No:
- Q9CRA0
- Immunogen:
- Synthetic peptide from human protein at AA range: 181-230
- Specificity:
- The antibody detects endogenous CD297
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31;ADP-ribosyltransferase C2 and C3 toxin-like 4;ARTC4;Dombrock blood group carrier molecule;Mono(ADP-ribosyl)transferase 4;NAD(P)(+)--arginine ADP-ribosyltransferase 4;CD antigen CD297)
- Background:
- This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008],
- Function:
- catalytic activity:NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine.,catalytic activity:NADP(+) + protein-L-arginine = nicotinamide + N(omega)-((2'-phospho-ADP)-D-ribosyl)-protein-L-arginine.,online information:Blood group antigen gene mutation database,polymorphism:DO is responsible for the Dombrock blood group system. The molecular basis of the Do(a)/Do(b) blood group antigen is a single variation in position 265; Asn-265 corresponds to Do(a) and Asp-265 to Do(b). It is also responsible for the antigens Gregory [Gy(a)], Holley [Hy] and Joseph [Jo(a)].,similarity:Belongs to the Arg-specific ADP-ribosyltransferase family.,tissue specificity:Expressed in spleen and T-cells.,
- Subcellular Location:
- Cell membrane; Lipid-anchor, GPI-anchor.
- Expression:
- Expressed in spleen and T-cells.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200