• Target：
• CD296

• Gene Name：
• ART1

• Protein Name：
• GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1

• Human Gene Id：
• 417

• Human Swiss Prot No：
• P52961

• Mouse Gene Id：
• 11870

• Mouse Swiss Prot No：
• Q60935

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human ART1. AA range:51-100

• Specificity：
• CD296 Polyclonal Antibody detects endogenous levels of CD296 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ART1;GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1;ADP-ribosyltransferase C2 and C3 toxin-like 1;ARTC1;Mono(ADP-ribosyl)transferase 1;CD296

• Observed Band(KD)：
• 37kD

• Background：
• ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008],

• Function：
• catalytic activity:NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine.,catalytic activity:NADP(+) + protein-L-arginine = nicotinamide + N(omega)-((2'-phospho-ADP)-D-ribosyl)-protein-L-arginine.,similarity:Belongs to the Arg-specific ADP-ribosyltransferase family.,

• Subcellular Location：
• Sarcoplasmic reticulum membrane; Lipid-anchor, GPI-anchor.

• Expression：
• Skeletal muscle,

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