• Target：
• Endoglycan

• Gene Name：
• PODXL2

• Protein Name：
• Podocalyxin-like protein 2

• Human Gene Id：
• 50512

• Human Swiss Prot No：
• Q9NZ53

• Mouse Swiss Prot No：
• Q8CAE9

• Immunogen：
• Synthesized peptide derived from the Internal region of human Endoglycan.

• Specificity：
• Endoglycan Polyclonal Antibody detects endogenous levels of Endoglycan protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PODXL2;Podocalyxin-like protein 2;Endoglycan

• Observed Band(KD)：
• 65kD

• Background：
• This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins. [provided by RefSeq, Oct 2012],

• Function：
• PTM:Glycosylated; contains chondroitin sulfate. Displays sialylated O-linked oligosaccharides.,PTM:Sulfation and sialylated O-linked oligosaccharides are necessary for SELL/L-selectin binding.,similarity:Belongs to the podocalyxin family.,subunit:Homodimer; disulfide-linked. Binds to SELL/L-selectin.,tissue specificity:Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells.,

• Subcellular Location：
• Membrane ; Single-pass type I membrane protein .

• Expression：
• Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells.

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