• Target：
• Neurotensin

• Fields：
• >>Neuroactive ligand-receptor interaction

• Gene Name：
• NTS

• Protein Name：
• Neurotensin/neuromedin N

• Human Gene Id：
• 4922

• Human Swiss Prot No：
• P30990

• Mouse Gene Id：
• 67405

• Mouse Swiss Prot No：
• Q9D3P9

• Rat Swiss Prot No：
• P20068

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the C-terminal region of human NTS. AA range:121-170

• Specificity：
• Neurotensin Polyclonal Antibody detects endogenous levels of Neurotensin protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NTS;Neurotensin/neuromedin N

• Observed Band(KD)：
• 20kD

• Background：
• This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014],

• Function：
• function:Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.,online information:Neurotensin entry,similarity:Belongs to the neurotensin family.,subcellular location:Packaged within secretory vesicles.,

• Subcellular Location：
• Secreted. Cytoplasmic vesicle, secretory vesicle. Packaged within secretory vesicles.

• Expression：
• Brain,Tongue,

Xiao, Ming, et al. "Early growth response 2 regulates mouse cooperative behavior." (2020).

Early growth response 2 in the mPFC regulates mouse social and cooperative behaviors LAB ANIMAL Chengyu Sheng WB Mouse Neuro-2a cell

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