Flt3-L Polyclonal Antibody

    • Catalog No.:YT5516
    • Applications:WB;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • Flt3-L
      • Fields:
      • >>MAPK signaling pathway;>>Ras signaling pathway;>>PI3K-Akt signaling pathway;>>Hematopoietic cell lineage;>>Pathways in cancer
      • Gene Name:
      • FLT3LG
      • Protein Name:
      • Fms-related tyrosine kinase 3 ligand
      • Human Gene Id:
      • 2323
      • Human Swiss Prot No:
      • P49771
      • Mouse Swiss Prot No:
      • P49772
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from the C-terminal region of human FLT3LG. AA range:171-220
      • Specificity:
      • Flt3-L Polyclonal Antibody detects endogenous levels of Flt3-L protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • FLT3LG;Fms-related tyrosine kinase 3 ligand;Flt3 ligand;Flt3L;SL cytokine
      • Observed Band(KD):
      • 26kD
      • Background:
      • Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011],
      • Function:
      • function:Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins.,subunit:Homodimer (isoform 2).,
      • Subcellular Location:
      • [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
      • Expression:
      • Brain,Spleen,
      • Products Images
      • Western Blot analysis of HeLa cells using Flt3-L Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000