Nov Polyclonal Antibody

    • Catalog No.:YT5412
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • Nov
      • Gene Name:
      • NOV
      • Protein Name:
      • Protein NOV homolog
      • Human Gene Id:
      • 4856
      • Human Swiss Prot No:
      • P48745
      • Mouse Swiss Prot No:
      • Q64299
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from the Internal region of human NOV. AA range:221-270
      • Specificity:
      • Nov Polyclonal Antibody detects endogenous levels of Nov protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • NOV;CCN3;IGFBP9;NOVH;Protein NOV homolog;NovH;CCN family member 3;Insulin-like growth factor-binding protein 9;IBP-9;IGF-binding protein 9;IGFBP-9;Nephroblastoma-overexpressed gene protein homolog
      • Observed Band(KD):
      • 39kD
      • Background:
      • The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009],
      • Function:
      • function:Immediate-early protein likely to play a role in cell growth regulation.,similarity:Belongs to the CCN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 TSP type-1 domain.,similarity:Contains 1 VWFC domain.,subunit:Interacts with FBLN1.,tissue specificity:Increased expression in Wilms tumor of the stromal type.,
      • Subcellular Location:
      • Secreted. Cytoplasm . Cell junction, gap junction . Localizes at the gap junction in presence of GJA1. .
      • Expression:
      • Expressed in endiothelial cells (at protein level) (PubMed:21063504). Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type.
      • Products Images
      • Western Blot analysis of MCF-7 cells using Nov Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Western blot analysis of lysate from MCF-7 cells, using NOV Antibody.