Nov Polyclonal Antibody
- Catalog No.:YT5412
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- Nov
- Gene Name:
- NOV
- Protein Name:
- Protein NOV homolog
- Human Gene Id:
- 4856
- Human Swiss Prot No:
- P48745
- Mouse Gene Id:
- 18133
- Mouse Swiss Prot No:
- Q64299
- Rat Gene Id:
- 81526
- Rat Swiss Prot No:
- Q9QZQ5
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human NOV. AA range:221-270
- Specificity:
- Nov Polyclonal Antibody detects endogenous levels of Nov protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- NOV;CCN3;IGFBP9;NOVH;Protein NOV homolog;NovH;CCN family member 3;Insulin-like growth factor-binding protein 9;IBP-9;IGF-binding protein 9;IGFBP-9;Nephroblastoma-overexpressed gene protein homolog
- Observed Band(KD):
- 39kD
- Background:
- The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009],
- Function:
- function:Immediate-early protein likely to play a role in cell growth regulation.,similarity:Belongs to the CCN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 TSP type-1 domain.,similarity:Contains 1 VWFC domain.,subunit:Interacts with FBLN1.,tissue specificity:Increased expression in Wilms tumor of the stromal type.,
- Subcellular Location:
- Secreted. Cytoplasm . Cell junction, gap junction . Localizes at the gap junction in presence of GJA1. .
- Expression:
- Expressed in endiothelial cells (at protein level) (PubMed:21063504). Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type.
- June 19-2018
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- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
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- May 20-2022
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- July 13-2018
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- July 13-2018
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- July 13-2018
- Antibody-FAQs
- Products Images
- Western Blot analysis of MCF-7 cells using Nov Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Western blot analysis of lysate from MCF-7 cells, using NOV Antibody.