SCYL1BP1 Polyclonal Antibody

    • Catalog No.:YT5369
    • Applications:WB,ELISA
    • Reactivity:Human,Mouse,Rat
      • Gene Name:
      • GORAB
      • Protein Name:
      • RAB6-interacting golgin
      • Human Swiss Prot No:
      • Q5T7V8
      • Mouse Swiss Prot No:
      • Q8BRM2
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from the N-terminal region of human GORAB. AA range:1-50
      • Specificity:
      • SCYL1BP1 Polyclonal Antibody detects endogenous levels of SCYL1BP1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • GORAB; NTKLBP1; SCYL1BP1; RAB6-interacting golgin; N-terminal kinase-like-binding protein 1; NTKL-BP1; NTKL-binding protein 1; hNTKL-BP1; SCY1-like 1-binding protein 1; SCYL1-BP1; SCYL1-binding protei
      • MolecularWeight(Da):
      • 44993
      • Observed Band(KD):
      • 45
      • Background:
      • golgin, RAB6 interacting(GORAB) Homo sapiens This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009],
      • Function:
      • caution:It is uncertain whether Met-1 or Met-26 is the initiator.,disease:Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.,similarity:Belongs to the GORAB family.,subunit:Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6.,
      • Subcellular Location:
      • nucleus,nucleoplasm,nucleolus,cytoplasm,Golgi apparatus,
      • Expression:
      • Embryo,Pancreas,Testis,Trachea,
      • Products Images
      • Western Blot analysis of AD293 cells using SCYL1BP1 Polyclonal Antibody.. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Western blot analysis of lysate from AD293 cells, using GORAB Antibody.