• Target：
• SCYL1BP1

• Fields：
• >>p53 signaling pathway

• Gene Name：
• GORAB

• Protein Name：
• RAB6-interacting golgin

• Human Gene Id：
• 92344

• Human Swiss Prot No：
• Q5T7V8

• Mouse Gene Id：
• 98376

• Mouse Swiss Prot No：
• Q8BRM2

• Rat Gene Id：
• 304923

• Rat Swiss Prot No：
• B1H222

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the N-terminal region of human GORAB. AA range:1-50

• Specificity：
• SCYL1BP1 Polyclonal Antibody detects endogenous levels of SCYL1BP1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GORAB;NTKLBP1;SCYL1BP1;RAB6-interacting golgin;N-terminal kinase-like-binding protein 1;NTKL-BP1;NTKL-binding protein 1;hNTKL-BP1;SCY1-like 1-binding protein 1;SCYL1-BP1;SCYL1-binding protein 1

• Observed Band(KD)：
• 45kD

• Background：
• golgin, RAB6 interacting(GORAB) Homo sapiens This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009],

• Function：
• caution:It is uncertain whether Met-1 or Met-26 is the initiator.,disease:Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.,similarity:Belongs to the GORAB family.,subunit:Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6.,

• Subcellular Location：
• Cytoplasm . Golgi apparatus .

• Expression：
• Embryo,Pancreas,Testis,Trachea,

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