• Target：
• PSP

• Gene Name：
• PSPN

• Protein Name：
• Persephin

• Human Gene Id：
• 5623

• Human Swiss Prot No：
• O60542

• Mouse Swiss Prot No：
• O70300

• Rat Gene Id：
• 25525

• Rat Swiss Prot No：
• O70301

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the C-terminal region of human PSPN. AA range:101-150

• Specificity：
• PSP Polyclonal Antibody detects endogenous levels of PSP protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PSPN;Persephin;PSP

• Observed Band(KD)：
• 16kD

• Background：
• persephin(PSPN) Homo sapiens This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016],

• Function：
• function:Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.,similarity:Belongs to the TGF-beta family. GDNF subfamily.,subunit:Homodimer; disulfide-linked.,

• Subcellular Location：
• Secreted.

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