• Target：
• HDC

• Fields：
• >>Histidine metabolism;>>Metabolic pathways

• Gene Name：
• HDC

• Protein Name：
• Histidine decarboxylase

• Human Gene Id：
• 3067

• Human Swiss Prot No：
• P19113

• Mouse Gene Id：
• 15186

• Mouse Swiss Prot No：
• P23738

• Rat Swiss Prot No：
• P16453

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human HDC. AA range:201-250

• Specificity：
• HDC Polyclonal Antibody detects endogenous levels of HDC protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• HDC;Histidine decarboxylase;HDC

• Observed Band(KD)：
• 72kD

• Background：
• This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010],

• Function：
• catalytic activity:L-histidine = histamine + CO(2).,cofactor:Pyridoxal phosphate.,pathway:Amine and polyamine biosynthesis; histamine biosynthesis; histamine from L-histidine: step 1/1.,similarity:Belongs to the group II decarboxylase family.,subunit:Homodimer.,

• Subcellular Location：
• cytosol,

• Expression：
• Leukemia,

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