• Target：
• Aldolase C

• Fields：
• >>Glycolysis / Gluconeogenesis;>>Pentose phosphate pathway;>>Fructose and mannose metabolism;>>Metabolic pathways;>>Carbon metabolism;>>Biosynthesis of amino acids;>>HIF-1 signaling pathway

• Gene Name：
• ALDOC

• Protein Name：
• Fructose-bisphosphate aldolase C

• Human Gene Id：
• 230

• Human Swiss Prot No：
• P09972

• Mouse Gene Id：
• 11676

• Mouse Swiss Prot No：
• P05063

• Rat Gene Id：
• 24191

• Rat Swiss Prot No：
• P09117

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the N-terminal region of human ALDOC. AA range:21-70

• Specificity：
• Aldolase C Polyclonal Antibody detects endogenous levels of Aldolase C protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ALDOC;ALDC;Fructose-bisphosphate aldolase C;Brain-type aldolase

• Observed Band(KD)：
• 39kD

• Background：
• This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008],

• Function：
• catalytic activity:D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.,miscellaneous:In vertebrates, three forms of this ubiquitous glycolytic enzyme are found, aldolase A in muscle, aldolase B in liver and aldolase C in brain.,pathway:Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.,similarity:Belongs to the class I fructose-bisphosphate aldolase family.,subunit:Homotetramer.,

• Subcellular Location：
• mitochondrion,cytosol,cytoskeleton,extracellular exosome,

• Expression：
• Brain,Colon,Epithelium,Eye,Uterus,

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