• Target：
• K-cadherin

• Gene Name：
• CDH6

• Protein Name：
• Cadherin-6

• Human Gene Id：
• 1004

• Human Swiss Prot No：
• P55285

• Mouse Gene Id：
• 12563

• Mouse Swiss Prot No：
• P97326

• Rat Gene Id：
• 25409

• Rat Swiss Prot No：
• P55280

• Immunogen：
• Synthesized peptide derived from K-cadherin . at AA range: 180-260

• Specificity：
• K-cadherin Polyclonal Antibody detects endogenous levels of K-cadherin protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CDH6;Cadherin-6;Kidney cadherin;K-cadherin

• Observed Band(KD)：
• 88kD

• Background：
• This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011],

• Function：
• function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.,

• Subcellular Location：
• Cell membrane; Single-pass type I membrane protein.

• Expression：
• Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.

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