• Target：
• RASSF8

• Gene Name：
• RASSF8

• Protein Name：
• Ras association domain-containing protein 8

• Human Gene Id：
• 11228

• Human Swiss Prot No：
• Q8NHQ8

• Mouse Swiss Prot No：
• Q8CJ96

• Immunogen：
• Synthesized peptide derived from RASSF8 . at AA range: 60-140

• Specificity：
• RASSF8 Polyclonal Antibody detects endogenous levels of RASSF8 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• RASSF8;C12orf2;Ras association domain-containing protein 8;Carcinoma-associated protein HOJ-1

• Observed Band(KD)：
• 48kD

• Background：
• This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],

• Function：
• disease:A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly, also referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses [MIM:608180]. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.,similarity:Contains 1 Ras-associating domain.,tissue specificity:Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis.,

• Expression：
• Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis.

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