• Target：
• BAGE5

• Gene Name：
• BAG5

• Protein Name：
• BAG family molecular chaperone regulator 5

• Human Gene Id：
• 9529

• Human Swiss Prot No：
• Q9UL15

• Mouse Gene Id：
• 70369

• Mouse Swiss Prot No：
• Q8CI32

• Rat Gene Id：
• 366734

• Rat Swiss Prot No：
• Q5QJC9

• Immunogen：
• Synthesized peptide derived from BAGE5 . at AA range: 30-110

• Specificity：
• BAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• BAG5;KIAA0873;BAG family molecular chaperone regulator 5;BAG-5;Bcl-2-associated athanogene 5

• Observed Band(KD)：
• 51kD

• Background：
• The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• Function：
• function:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2.,similarity:Contains 4 BAG domains.,subunit:Binds to the ATPase domain of HSP70/HSC chaperones. Binds PARK2.,

• Subcellular Location：
• nucleus,mitochondrion,cytosol,membrane,inclusion body,perinuclear region of cytoplasm,

• Expression：
• Brain,

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