• Target：
• ZHX2

• Gene Name：
• ZHX2

• Protein Name：
• Zinc fingers and homeoboxes protein 2

• Human Gene Id：
• 22882

• Human Swiss Prot No：
• Q9Y6X8

• Mouse Gene Id：
• 387609

• Mouse Swiss Prot No：
• Q8C0C0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human ZHX2. AA range:751-800

• Specificity：
• ZHX2 Polyclonal Antibody detects endogenous levels of ZHX2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ZHX2;AFR1;KIAA0854;RAF;Zinc fingers and homeoboxes protein 2;Alpha-fetoprotein regulator 1;AFP regulator 1;Regulator of AFP;Zinc finger and homeodomain protein 2

• Observed Band(KD)：
• 92kD

• Background：
• The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008],

• Function：
• function:Acts as a transcriptional repressor.,similarity:Belongs to the ZHX family.,similarity:Contains 2 C2H2-type zinc fingers.,similarity:Contains 4 homeobox DNA-binding domains.,subunit:Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.,tissue specificity:Ubiquitously expressed.,

• Subcellular Location：
• Nucleus . Colocalizes with EFNB1 intracellular domain in the nucleus. .

• Expression：
• Ubiquitously expressed. Expressed in podocytes.

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