WAVE3 Polyclonal Antibody

    • Catalog No.:YT4899
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • WAVE3
      • Fields:
      • >>Adherens junction;>>Fc gamma R-mediated phagocytosis;>>Pathogenic Escherichia coli infection;>>Salmonella infection;>>Choline metabolism in cancer
      • Gene Name:
      • WASF3
      • Protein Name:
      • Wiskott-Aldrich syndrome protein family member 3
      • Human Swiss Prot No:
      • Q9UPY6
      • Mouse Swiss Prot No:
      • Q8VHI6
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human WASF3. AA range:151-200
      • Specificity:
      • WAVE3 Polyclonal Antibody detects endogenous levels of WAVE3 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • WASF3;KIAA0900;SCAR3;WAVE3;Wiskott-Aldrich syndrome protein family member 3;WASP family protein member 3;Protein WAVE-3;Verprolin homology domain-containing protein 3
      • Observed Band(KD):
      • 55kD
      • Background:
      • This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014],
      • Function:
      • domain:Binds the Arp2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain.,function:Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.,similarity:Belongs to the SCAR/WAVE family.,similarity:Contains 1 WH2 domain.,subunit:Binds actin and the Arp2/3 complex.,tissue specificity:Expressed in ovary and brain.,
      • Subcellular Location:
      • Cytoplasm, cytoskeleton.
      • Expression:
      • Expressed in ovary and brain.
      • Products Images
      • Western Blot analysis of 3T3 cells using WAVE3 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Western blot analysis of WASF3 Antibody. The lane on the right is blocked with the WASF3 peptide.
      • #N/A
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using WASF3 Antibody. The picture on the right is blocked with the synthesized peptide.