V-ATPase D Polyclonal Antibody

    • Catalog No.:YT4860
    • Applications:WB,ELISA
    • Reactivity:Human,Mouse,Rat
      • Gene Name:
      • ATP6V1D
      • Protein Name:
      • V-type proton ATPase subunit D
      • Human Swiss Prot No:
      • Q9Y5K8
      • Mouse Swiss Prot No:
      • P57746
      • Immunogen:
      • Synthesized peptide derived from V-ATPase D . at AA range: 70-150
      • Specificity:
      • V-ATPase D Polyclonal Antibody detects endogenous levels of V-ATPase D protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • ATP6V1D; ATP6M; VATD; V-type proton ATPase subunit D; V-ATPase subunit D; V-ATPase 28 kDa accessory protein; Vacuolar proton pump subunit D
      • MolecularWeight(Da):
      • 28263
      • Observed Band(KD):
      • 28
      • Background:
      • ATPase H+ transporting V1 subunit D(ATP6V1D) Homo sapiens This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.,similarity:Belongs to the V-ATPase D subunit family.,subunit:V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).,
      • Subcellular Location:
      • lysosomal membrane,centrosome,cytosol,cilium,membrane,proton-transporting V-type ATPase complex,extracellular exosome,
      • Expression:
      • Bone marrow,Brain,Heart,Pancreatic adenocarcinoma,Pituitary,Placent
      • Products Images
      • Western blot analysis of ATP6V1D Antibody. The lane on the right is blocked with the ATP6V1D peptide.