• Target：
• USP40

• Gene Name：
• USP40

• Protein Name：
• Ubiquitin carboxyl-terminal hydrolase 40

• Human Gene Id：
• 55230

• Human Swiss Prot No：
• Q9NVE5

• Mouse Swiss Prot No：
• Q8BWR4

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human USP40. AA range:1011-1060

• Specificity：
• USP40 Polyclonal Antibody detects endogenous levels of USP40 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• USP40;Ubiquitin carboxyl-terminal hydrolase 40;Deubiquitinating enzyme 40;Ubiquitin thioesterase 40;Ubiquitin-specific-processing protease 40

• Observed Band(KD)：
• 140kD

• Background：
• Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],

• Function：
• catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May be catalytically inactive.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Broadly expressed.,

• Subcellular Location：
• nucleus,cytoplasm,

• Expression：
• Broadly expressed.

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