• Target：
• UMP-CMP Kinase

• Fields：
• >>Pyrimidine metabolism;>>Drug metabolism - other enzymes;>>Metabolic pathways;>>Nucleotide metabolism;>>Biosynthesis of cofactors

• Gene Name：
• CMPK1

• Protein Name：
• UMP-CMP kinase

• Human Gene Id：
• 51727

• Human Swiss Prot No：
• P30085

• Mouse Gene Id：
• 66588

• Mouse Swiss Prot No：
• Q9DBP5

• Rat Gene Id：
• 298410

• Rat Swiss Prot No：
• Q4KM73

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human KCY. AA range:1-50

• Specificity：
• UMP-CMP Kinase Polyclonal Antibody detects endogenous levels of UMP-CMP Kinase protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CMPK1;CMK;CMPK;UCK;UMK;UMPK;UMP-CMP kinase;Cytidine monophosphate kinase;Cytidylate kinase;Deoxycytidylate kinase;Uridine monophosphate kinase;Uridine monophosphate/cytidine monophosphate kinase;UMP/CMP kinase;UMP/CMPK

• Observed Band(KD)：
• 22kD

• Background：
• This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012],

• Function：
• catalytic activity:ATP + (d)CMP = ADP + (d)CDP.,cofactor:Magnesium.,function:Catalyzes specific phosphoryl transfer from ATP to UMP and CMP.,similarity:Belongs to the adenylate kinase family.,subcellular location:Mainly nuclear.,tissue specificity:Ubiquitously expressed.,

• Subcellular Location：
• Nucleus . Cytoplasm . Predominantly cytoplasmic, less than 15% nuclear. .

• Expression：
• Ubiquitously expressed.

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