• Target：
• TNF-IP 1

• Gene Name：
• TNFAIP1

• Protein Name：
• BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

• Human Gene Id：
• 7126

• Human Swiss Prot No：
• Q13829

• Mouse Gene Id：
• 21927

• Mouse Swiss Prot No：
• O70479

• Rat Gene Id：
• 287543

• Rat Swiss Prot No：
• Q7TNY1

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TNAP1. AA range:71-120

• Specificity：
• TNF-IP 1 Polyclonal Antibody detects endogenous levels of TNF-IP 1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TNFAIP1;BACURD2;EDP1;BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2;hBACURD2;BTB/POZ domain-containing protein TNFAIP1;Protein B12;Tumor necrosis factor; alpha-induced protein 1, endothelial

• Observed Band(KD)：
• 34kD

• Background：
• This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008],

• Function：
• function:Enhances the PCNA-dependent DNA polymerase delta activity.,induction:By TNF-alpha, interleukin-1 beta and lipopolysaccharide (LPS).,similarity:Belongs to the KCTD10/KCTD13/TNFAIP1 family.,similarity:Contains 1 BTB (POZ) domain.,subunit:Interacts with PCNA.,

• Subcellular Location：
• Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes.

• Expression：
• Amygdala,Endothelial cell,Epithelium,Lung,

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