TMEM145 Polyclonal Antibody

    • Catalog No.:YT4678
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • TMEM145
      • Gene Name:
      • TMEM145
      • Protein Name:
      • Transmembrane protein 145
      • Human Swiss Prot No:
      • Q8NBT3
      • Mouse Swiss Prot No:
      • Q8C4U2
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human TMEM145. AA range:58-107
      • Specificity:
      • TMEM145 Polyclonal Antibody detects endogenous levels of TMEM145 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • TMEM145;Transmembrane protein 145
      • Observed Band(KD):
      • 56kD
      • Background:
      • TMEM145 (transmembrane protein 145) is a 493 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.
      • Subcellular Location:
      • Membrane ; Multi-pass membrane protein .
      • Expression:
      • Retinoblastoma,
      • Products Images
      • Western Blot analysis of various cells using TMEM145 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Western blot analysis of lysates from HepG2 cells, using TMEM145 Antibody. The lane on the right is blocked with the synthesized peptide.