• Target：
• TMEM145

• Gene Name：
• TMEM145

• Protein Name：
• Transmembrane protein 145

• Human Gene Id：
• 284339

• Human Swiss Prot No：
• Q8NBT3

• Mouse Gene Id：
• 330485

• Mouse Swiss Prot No：
• Q8C4U2

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TMEM145. AA range:58-107

• Specificity：
• TMEM145 Polyclonal Antibody detects endogenous levels of TMEM145 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TMEM145;Transmembrane protein 145

• Observed Band(KD)：
• 56kD

• Background：
• TMEM145 (transmembrane protein 145) is a 493 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

• Subcellular Location：
• Membrane ; Multi-pass membrane protein .

• Expression：
• Retinoblastoma,

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