Tip5 Polyclonal Antibody

    • Catalog No.:YT4663
    • Applications:WB;IHC
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • Tip5
      • Gene Name:
      • BAZ2A
      • Protein Name:
      • Bromodomain adjacent to zinc finger domain protein 2A
      • Human Swiss Prot No:
      • Q9UIF9
      • Mouse Swiss Prot No:
      • Q91YE5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human BAZ2A. AA range:1281-1330
      • Specificity:
      • Tip5 Polyclonal Antibody detects endogenous levels of Tip5 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC-p 1:50-300
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • BAZ2A;KIAA0314;TIP5;Bromodomain adjacent to zinc finger domain protein 2A;Transcription termination factor I-interacting protein 5;TTF-I-interacting protein 5;Tip5;hWALp3
      • Observed Band(KD):
      • 210kD
      • Background:
      • function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 4 A.T hook DNA-binding domains.,subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus.,subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex).,tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.,
      • Function:
      • function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 4 A.T hook DNA-binding domains.,subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus.,subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex).,tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney
      • Subcellular Location:
      • Nucleus, nucleolus . Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. .
      • Expression:
      • Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.
      • Products Images
      • Western blot analysis of the lysates from HeLa cells using BAZ2A antibody.
      • Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).