• Target：
• Tip5

• Gene Name：
• BAZ2A

• Protein Name：
• Bromodomain adjacent to zinc finger domain protein 2A

• Human Gene Id：
• 605682

• Human Swiss Prot No：
• Q9UIF9

• Mouse Swiss Prot No：
• Q91YE5

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human BAZ2A. AA range:1281-1330

• Specificity：
• Tip5 Polyclonal Antibody detects endogenous levels of Tip5 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• BAZ2A;KIAA0314;TIP5;Bromodomain adjacent to zinc finger domain protein 2A;Transcription termination factor I-interacting protein 5;TTF-I-interacting protein 5;Tip5;hWALp3

• Observed Band(KD)：
• 210kD

• Background：
• function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 4 A.T hook DNA-binding domains.,subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus.,subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex).,tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.,

• Function：
• function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 4 A.T hook DNA-binding domains.,subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus.,subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex).,tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney

• Subcellular Location：
• Nucleus, nucleolus . Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. .

• Expression：
• Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.

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