TG1019 Polyclonal Antibody

    • Catalog No.:YT4624
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • TG1019
      • Gene Name:
      • OXER1
      • Protein Name:
      • Oxoeicosanoid receptor 1
      • Human Swiss Prot No:
      • Q8TDS5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human OXER1. AA range:212-261
      • Specificity:
      • TG1019 Polyclonal Antibody detects endogenous levels of TG1019 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • OXER1;GPR170;TG1019;Oxoeicosanoid receptor 1;5-oxo-ETE G-protein coupled receptor;G-protein coupled receptor 170;G-protein coupled receptor R527;G-protein coupled receptor TG1019
      • Observed Band(KD):
      • 46kD
      • Background:
      • function:Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages.,
      • Function:
      • function:Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages.,
      • Subcellular Location:
      • Cell membrane; Multi-pass membrane protein.
      • Expression:
      • Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages.
      • Products Images
      • Western Blot analysis of various cells using TG1019 Polyclonal Antibody
      • Immunofluorescence analysis of MCF7 cells, using OXER1 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from MCF-7 and Jurkat cells, using OXER1 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HUVECcells using OXER1 antibody.