TALK-2 Polyclonal Antibody

    • Catalog No.:YT4539
    • Applications:WB,ELISA
    • Reactivity:Human
      • Gene Name:
      • KCNK17
      • Protein Name:
      • Potassium channel subfamily K member 17
      • Human Swiss Prot No:
      • Q96T54
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human KCNK17. AA range:271-320
      • Specificity:
      • TALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • KCNK17; TALK2; TASK4; Potassium channel subfamily K member 17; 2P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; TWIK-related acid-sensitive K(+) channel 4; TWIK-rel
      • MolecularWeight(Da):
      • 36895
      • Observed Band(KD):
      • 40
      • Background:
      • potassium two pore domain channel subfamily K member 17(KCNK17) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
      • Function:
      • function:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.,miscellaneous:Inhibited by Ba(2+), quinidine, chloroform and halothane. Activated at alkaline pH. Activated by quinine and isoflurane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,
      • Subcellular Location:
      • plasma membrane,integral component of plasma membrane,integral component of membrane,
      • Expression:
      • Adrenal gland,Lung,Pancreas,Spleen,
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, using KCNK17 Antibody. The lane on the right is blocked with the synthesized peptide.