• Target：
• SR-5A

• Fields：
• >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction;>>Serotonergic synapse

• Gene Name：
• HTR5A

• Protein Name：
• 5-hydroxytryptamine receptor 5A

• Human Gene Id：
• 3361

• Human Swiss Prot No：
• P47898

• Mouse Swiss Prot No：
• P30966

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human HTR5A. AA range:15-64

• Specificity：
• SR-5A Polyclonal Antibody detects endogenous levels of SR-5A protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• HTR5A;5-hydroxytryptamine receptor 5A;5-HT-5;5-HT-5A;5-HT5A;Serotonin receptor 5A

• Observed Band(KD)：
• 36kD

• Background：
• The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008],

• Function：
• function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Brain,Cerebellum,

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