SPZ1 Polyclonal Antibody

    • Catalog No.:YT4390
    • Applications:IHC-p,IF,WB,ELISA
    • Reactivity:Human
      • Gene Name:
      • SPZ1
      • Protein Name:
      • Spermatogenic leucine zipper protein 1
      • Human Swiss Prot No:
      • Q9BXG8
      • Mouse Swiss Prot No:
      • Q99MY0
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SPZ1. AA range:111-160
      • Specificity:
      • SPZ1 Polyclonal Antibody detects endogenous levels of SPZ1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • SPZ1; TSP1; Spermatogenic leucine zipper protein 1; Testis-specific protein 1; Testis-specific protein NYD-TSP1
      • MolecularWeight(Da):
      • 133357
      • Observed Band(KD):
      • 133
      • Background:
      • spermatogenic leucine zipper 1(SPZ1) Homo sapiens This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011],
      • Function:
      • function:Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.,PTM:Phosphorylated by ERK1 and ERK2.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with PPP1CC isoform gamma-2.,tissue specificity:Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.,
      • Subcellular Location:
      • nucleus,cytoplasm,
      • Expression:
      • Brain,Testis,
      • Products Images
      • Immunofluorescence analysis of A549 cells, using SPZ1 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human testis tissue, using SPZ1 Antibody. The picture on the right is blocked with the synthesized peptide.