SPZ1 Polyclonal Antibody
- Catalog No.:YT4390
- Applications:IHC;IF;WB;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- SPZ1
- Gene Name:
- SPZ1
- Protein Name:
- Spermatogenic leucine zipper protein 1
- Human Gene Id:
- 84654
- Human Swiss Prot No:
- Q9BXG8
- Mouse Swiss Prot No:
- Q99MY0
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SPZ1. AA range:111-160
- Specificity:
- SPZ1 Polyclonal Antibody detects endogenous levels of SPZ1 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- SPZ1;TSP1;Spermatogenic leucine zipper protein 1;Testis-specific protein 1;Testis-specific protein NYD-TSP1
- Observed Band(KD):
- 133kD
- Background:
- This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011],
- Function:
- function:Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.,PTM:Phosphorylated by ERK1 and ERK2.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with PPP1CC isoform gamma-2.,tissue specificity:Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.,
- Subcellular Location:
- Cytoplasm . Nucleus .
- Expression:
- Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.
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- Antibody-FAQs
- Products Images
- Immunofluorescence analysis of A549 cells, using SPZ1 Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human testis tissue, using SPZ1 Antibody. The picture on the right is blocked with the synthesized peptide.