• Target：
• Septin 1

• Fields：
• >>Bacterial invasion of epithelial cells

• Gene Name：
• SEPT1

• Protein Name：
• Septin-1

• Human Gene Id：
• 1731

• Human Swiss Prot No：
• Q8WYJ6

• Mouse Gene Id：
• 54204

• Mouse Swiss Prot No：
• P42209

• Rat Gene Id：
• 293507

• Rat Swiss Prot No：
• Q5EB96

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human SEPT1. AA range:181-230

• Specificity：
• Septin 1 Polyclonal Antibody detects endogenous levels of Septin 1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SEPT1;DIFF6;PNUTL3;Septin-1;LARP;Peanut-like protein 3;Serologically defined breast cancer antigen NY-BR-24

• Observed Band(KD)：
• 41kD

• Background：
• septin 1(SEPT1) Homo sapiens This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012],

• Function：
• function:Involved in cytokinesis .,similarity:Belongs to the septin family.,subunit:May assemble into a multicomponent structure.,

• Subcellular Location：
• Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.

• Expression：
• Expressed at high levels in lymphoid and hematopoietic tissues.

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