• Target：
• S-100A10

• Fields：
• >>Salmonella infection

• Gene Name：
• S100A10

• Protein Name：
• Protein S100-A10

• Human Gene Id：
• 6281

• Human Swiss Prot No：
• P60903

• Mouse Gene Id：
• 20194

• Mouse Swiss Prot No：
• P08207

• Rat Gene Id：
• 81778

• Rat Swiss Prot No：
• P05943

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human S-100A10. AA range:3-52

• Specificity：
• S-100A10 Polyclonal Antibody detects endogenous levels of S-100A10 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• S100A10;ANX2LG;CAL1L;CLP11;Protein S100-A10;Calpactin I light chain;Calpactin-1 light chain;Cellular ligand of annexin II;S100 calcium-binding protein A10;p10 protein;p11

• Observed Band(KD)：
• 11kD

• Background：
• The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008],

• Function：
• function:Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.,miscellaneous:Does not appear to bind calcium. Contains 2 ancestral calcium site related to EF-hand domains that have lost their ability to bind calcium.,similarity:Belongs to the S-100 family.,subunit:Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A.,

• Subcellular Location：
• integral component of membrane,extrinsic component of plasma membrane,membrane raft,extracellular exosome,

• Expression：
• Brain,Keratinocyte,

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Bruton’s tyrosine kinase-bearing B cells and microglia in neuromyelitis optica spectrum disorder Journal of Neuroinflammation Liu Ye IF Mouse 1:500 brain tissue

Buyang Huanwu Decoction promotes neurovascular remodeling by modulating astrocyte and microglia polarization in ischemic stroke rats JOURNAL OF ETHNOPHARMACOLOGY Ming-cong Li IF,WB Rat brain cortex

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