Rho GDIγ Polyclonal Antibody

    • Catalog No.:YT4082
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • Rho GDIγ
      • Fields:
      • >>Neurotrophin signaling pathway;>>Vasopressin-regulated water reabsorption
      • Gene Name:
      • ARHGDIG
      • Protein Name:
      • Rho GDP-dissociation inhibitor 3
      • Human Gene Id:
      • 398
      • Human Swiss Prot No:
      • Q99819
      • Mouse Swiss Prot No:
      • Q62160
      • Immunogen:
      • Synthesized peptide derived from Rho GDIγ . at AA range: 110-190
      • Specificity:
      • Rho GDIγ Polyclonal Antibody detects endogenous levels of Rho GDIγ protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • ARHGDIG;Rho GDP-dissociation inhibitor 3;Rho GDI 3;Rho-GDI gamma
      • Observed Band(KD):
      • 25kD
      • Background:
      • The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010],
      • Function:
      • function:Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.,similarity:Belongs to the Rho GDI family.,tissue specificity:Primarily expressed in pancreas and brain.,
      • Subcellular Location:
      • Cytoplasm.
      • Expression:
      • Primarily expressed in pancreas and brain.
      • Products Images
      • Western Blot analysis of various cells using Rho GDIγ Polyclonal Antibody
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).