• Target：
• RACK7

• Gene Name：
• ZMYND8

• Protein Name：
• Protein kinase C-binding protein 1

• Human Gene Id：
• 23613

• Human Swiss Prot No：
• Q9ULU4

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human PKCB1. AA range:581-630

• Specificity：
• RACK7 Polyclonal Antibody detects endogenous levels of RACK7 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ZMYND8;KIAA1125;PRKCBP1;RACK7;Protein kinase C-binding protein 1;Cutaneous T-cell lymphoma-associated antigen se14-3;CTCL-associated antigen se14-3;Rack7;Zinc finger MYND domain-containing protein 8

• Observed Band(KD)：
• 132kD

• Background：
• The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• Function：
• PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,subunit:Interacts in vitro with PRKCB1.,tissue specificity:Expressed in all tissues examined with highest expression in brain, lung, pancreas, and placenta. Expressed in cutaneous T-cell lymphomas (CTCL).,

• Subcellular Location：
• Nucleus . Cytoplasm . Sequestered in the cytoplasm through the interaction with DBN1. .

• Expression：
• Expressed in all tissues examined with highest expression in brain, lung, pancreas, and placenta. Expressed in cutaneous T-cell lymphomas (CTCL).

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