Rab 2B Polyclonal Antibody

    • Catalog No.:YT3925
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Rab 2B
      • Gene Name:
      • RAB2B
      • Protein Name:
      • Ras-related protein Rab-2B
      • Human Swiss Prot No:
      • Q8WUD1
      • Mouse Swiss Prot No:
      • P59279
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human RAB2B. AA range:103-152
      • Specificity:
      • Rab 2B Polyclonal Antibody detects endogenous levels of Rab 2B protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • RAB2B;Ras-related protein Rab-2B
      • Observed Band(KD):
      • 24kD
      • Background:
      • Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006],
      • Function:
      • function:Required for protein transport from the endoplasmic reticulum to the Golgi complex .,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte.,
      • Subcellular Location:
      • Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endoplasmic reticulum membrane ; Lipid-anchor . Golgi apparatus membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle, acrosome . Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid. .
      • Expression:
      • Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte.
      • Products Images
      • Western blot analysis of RAB2B Antibody. The lane on the right is blocked with the RAB2B peptide.
      • Western blot analysis of the lysates from 293 cells using RAB2B antibody.
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).