• Target：
• PSK2

• Fields：
• >>MAPK signaling pathway

• Gene Name：
• TAOK1

• Protein Name：
• Serine/threonine-protein kinase TAO1

• Human Gene Id：
• 57551

• Human Swiss Prot No：
• Q7L7X3

• Mouse Gene Id：
• 216965

• Mouse Swiss Prot No：
• Q5F2E8

• Rat Gene Id：
• 286993

• Rat Swiss Prot No：
• O88664

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TAOK1. AA range:431-480

• Specificity：
• PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TAOK1;KIAA1361;MAP3K16;MARKK;Serine/threonine-protein kinase TAO1;Kinase from chicken homolog B;hKFC-B;MARK Kinase;MARKK;Prostate-derived sterile 20-like kinase 2;PSK-2;PSK2;Prostate-derived STE20-like kinase 2;Thousand and one

• Observed Band(KD)：
• 120kD

• Background：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,

• Function：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.

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